Authors compared the various imaging techniques including application of magnetization transfer(MT), administration of IV contrast materials, and imaging time after injection of contrast materials in 3D time-of-flight(TOF) cerebral magnetic
resonance
angiography(MRA) in normal volunteers. Each of 11 healthy volunteers was prospectively studied with 3D TOF cerebral MRA using various imaging parameters. Various parameters of 3D TOF MRA were 1) preenhanced magnetization transfer(MT), 2)
postenhanced
MT, immediate phase, 3) postenhanced MT, 10-minutes delayed phase, 4) postenhanced MT, 20-minutes delayed phase, 5) pre-enhanced non-MT 6) postenhanced non-MT, immediate phase, 7) postenhanced non-MT, 10-minutes delayed phase, 8) postenhanced
non-MT,
20-minutes delayed phase. Image qualities of various parameters were compared with regard to depiction of cerebra arteries and veins by visual assessment, For staistical analysis paired t-test was used. In pre-enhanced MRA, images with MT mode
were
better in arterial visualization than those with non-MT mode(p<0.01). Postenhanced MT and non-MT images were better in arterial and venous visualization than enhanced MT and non-MT images(p<0.01) respectively. Images obtained immediately after
injection
of contrast were better in both arterial and venous visualization than those delayed images(p<0.01). Postenhanced cerebral 3D TOF MRA with MT obtained immeditely after injection of contrast materal is the best to increase visualization of both
cerebral
arteries and veins, and may be indicated some intracranial vascular diseases.
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